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Neuromedin

  • Living reference work entry
  • First Online:
Encyclopedia of Cancer
  • 24 Accesses

Definition

A family of peptides that comprises the neuromedins A, B, and C (bombesin-like), K (neurokinin B) and L (neurokinin A), N (neurotensin-like), S, and U.

Characteristics

This family of peptides termed “neuromedins” was initially isolated from porcine spinal cord on account of its ability to contract smooth muscle. This family of peptides currently includes the neuromedins A (NMA), B (NMB), C (NMC), K (NMK), L (NML), N (NMN), S (NMS), and U (NMU); however, their structural and functional characteristics vary greatly. These neuromedins are found in many tissues including the central nervous system as well as in the gastrointestinal tract and have been implicated in a wide variety of physiological functions as neuropeptides. Neuropeptides function peripherally as paracrine and autocrine factors to regulate diverse physiological processes and act as neurotransmitters or neuromodulators in the nervous system. In general, the receptors which mediate signaling by binding...

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See Also

  • (2012) Autocrine. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 311. doi: 10.1007/978-3-642-16483-5_468

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  • (2012) Glioma. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 1557. doi: 10.1007/978-3-642-16483-5_2423

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  • (2012) Paracrine. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 2783. doi: 10.1007/978-3-642-16483-5_4380

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Correspondence to Yataro Daigo .

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© 2015 Springer-Verlag Berlin Heidelberg

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Daigo, Y. (2015). Neuromedin. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_4040-2

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  • DOI: https://doi.org/10.1007/978-3-642-27841-9_4040-2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27841-9

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