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Neuroendocrine Carcinoma

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Synonyms

Apudomas; Carcinoid tumors; Islet cell tumors; Malignant endocrine tumors; Neuroendocrine tumors of the pancreas

Definition

Neuroendocrine carcinomas are tumors derived from the diffuse neuroendocrine system.

Characteristics

Neuroendocrine carcinomas will include a heterogeneous group of tumors that can arise wherever the diffuse neuroendocrine system is found throughout the body.

Classification

It is widely accepted to divide these malignancies in two major groups: carcinoid tumors and neuroendocrine tumors of the pancreas. There are other, rare malignancies that also are classified as neuroendocrine carcinomas, including pheochromocytomas, medullary thyroid carcinoma, and Merkel cell tumors.

Other subclassifications will consider these tumors according to site of origin (lung, gastrointestinal tract, etc.), capability of producing certain hormones (functioning and nonfunctioning tumors), degree of cellular differentiation as an indicator of biological aggressiveness (well,...

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References

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Correspondence to Ignacio Duran .

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Duran, I., Siu, L.L. (2014). Neuroendocrine Carcinoma. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_4029-4

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  • DOI: https://doi.org/10.1007/978-3-642-27841-9_4029-4

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