Neoadjuvant therapy is an auxiliary therapy (e.g., androgen ablation in prostate cancer) administered prior to another therapy (e.g., surgery or radiation). It is given prior to surgery in an attempt to decrease the size of the tumor. It is performed in an attempt to make the tumor easier to remove and to increase the chances that removal of the tumor is curative.
Downstaging of the tumor allowing for less extensive surgery to be performed
KeywordsSystemic Therapy Breast Conservation Surgery Androgen Ablation Fine Needle Aspirate Primary Systemic Therapy
- (2012) Ablation. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 14. doi: 10.1007/978-3-642-16483-5_16Google Scholar