Monoclonal Gammopathy of Undetermined Significance (MGUS)
Monoclonal gammopathy of unknown significance and monoclonal gammopathy of uncertain significance are synonyms. MGUS was formerly known as benign monoclonal gammopathy (BMG), but usage of this term has been discouraged because it implies that the condition is not harmful in effect. To highlight recent findings that MGUS may cause kidney and skeletal damage in a subset of patients, the term has been modified in the biomedical literature to monoclonal gammopathy of renal significance and monoclonal gammopathy of skeletal significance, respectively.
KeywordsSpinal Muscular Atrophy Polycythemia Vera Pyoderma Gangrenosum Hairy Cell Leukemia Monoclonal Gammopathy
- Landgren O (2013) Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma: biological insights and early treatment strategies. Hematol Am Soc Hematol Educ Program 2013:478–87Google Scholar
- (2012) POEMS syndrome. In: Schwab M (ed) Encyclopedia of cancer. Springer, Berlin/Heidelberg, p 2934. doi:10.1007/978-3-642-16483-5_4652Google Scholar