Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Molecular Imaging

  • Tobias Bäuerle
  • Wolfhard Semmler
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_3813-6

Definition

Molecular imaging is an interdisciplinary approach to noninvasively assess disease-specific structures in a living organism. When using the term molecular imaging in the narrow sense, imaging of molecular structures is referred to, but in the broader sense also, the assessment of morphology in high resolution; functional and metabolic parameters are included. When applying the broader definition, the following imaging techniques are most relevant: magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), computed tomography (CT), ultrasound (US), optical imaging (OI), positron emission tomography (PET), and single-photon emission computed tomography (SPECT). Each imaging modality produces data with advantages and disadvantages containing complementary information from a region of interest. For probe design, data acquisition, and image postprocessing, knowledge from biology, chemistry, physics, pharmacology, informatics, and medicine is required. MR...

Keywords

Positron Emission Tomography Molecular Imaging High Resolution Compute Tomography Bioluminescence Imaging Molecular Imaging Technique 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. Semmler W (2008) Molecular imaging. In: Reiser MF, Semmler W, Hricak H (eds) Magnetic resonance tomography, 3rd edn. Springer, Heidelberg, pp 1381–1410CrossRefGoogle Scholar
  2. Thakur M, Lentle BC (2005) Report of a summit on molecular imaging. Radiology 236:753–755CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Institute of RadiologyUniversity Medical Center ErlangenErlangenGermany
  2. 2.Department of Medical Physics in RadiologyGerman Cancer Research CenterHeidelbergGermany