Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Appendiceal Epithelial Neoplasms

  • Paul H. Sugarbaker
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_370-2

Synonyms

Definition

Appendiceal epithelial neoplasms include a broad spectrum of tumors that vary greatly in their biological aggressiveness. Usually, they produce copious mucus as do normal appendiceal epithelial cells. The tumors usually rupture the wall of the appendix prior to diagnosis causing widespread peritoneal dissemination of the disease. New treatment options are directed at definitive treatment of the peritoneal surface component of this disease which will cause death from intestinal dysfunction unless properly managed.

Characteristics

Epithelial Appendiceal Neoplasms

Table 1summarizes the unique characteristics of these tumors and contrasts them with colorectal...

Keywords

Peritoneal Carcinomatosis Cytoreductive Surgery Peritoneal Dissemination Intraperitoneal Chemotherapy Peritoneal Surface 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. Carmignani P, Sugarbaker TA, Bromley CM et al (2003) Intraperitoneal cancer dissemination: mechanisms of the patterns of spread. Cancer Metastasis Rev 22:465–472CrossRefPubMedGoogle Scholar
  2. Esquivel J, Sugarbaker PH (2000) Clinical presentation of the pseudomyxoma peritonei syndrome. Br J Surg 87:1414–1418CrossRefPubMedGoogle Scholar
  3. Farquarson AL, Pranesh N, Witham G et al (2008) A phase 11 study evaluating the use of concurrent mitomysin C and capecitabine in patients with advanced unresectable pseudomyxoma peritonei. Br J Cancer 99:591–596CrossRefGoogle Scholar
  4. Gonzalez-Moreno S, Sugarbaker PH (2004) Right hemicolectomy does not confer a survival advantage in patients with mucinous carcinoma of the appendix and peritoneal seeding. Br J Surg 91:304–311CrossRefPubMedGoogle Scholar
  5. Rout S, Renehan AG, Parkinson M et al (2009) The treatment and outcomes of peritoneal surface tumors through a national service UK. Dis Colon Rectum 52:1705–1714Google Scholar
  6. Sugarbaker PH (1995) Peritonectomy procedures. Ann Surg 221:29–42PubMedCentralCrossRefPubMedGoogle Scholar
  7. Sugarbaker PH (2006) New standard of care for appendiceal epithelial malignancies and pseudomyxoma peritonei syndrome. Lancet Oncol 7:69–76CrossRefPubMedGoogle Scholar

See Also

  1. (2012) Adenocarcinoid. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 48. doi:10.1007/978-3-642-16483-5_83Google Scholar
  2. (2012) Adenomucinosis. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 48. doi:10.1007/978-3-642-16483-5_88Google Scholar
  3. (2012) Adjuvant. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 75. doi:10.1007/978-3-642-16483-5_107Google Scholar
  4. (2012) Complete cytoreduction. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 964. doi:10.1007/978-3-642-16483-5_1290Google Scholar
  5. (2012) Cytoreduction. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 1056–1057. doi:10.1007/978-3-642-16483-5_1488Google Scholar
  6. (2012) Doxorubicin. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1159. doi:10.1007/978-3-642-16483-5_1722Google Scholar
  7. (2012) 5-Fluorouracil. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1429. doi:10.1007/978-3-642-16483-5_2223Google Scholar
  8. (2012) Intestinal type adenocarcinoma. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1900. doi:10.1007/978-3-642-16483-5_3116Google Scholar
  9. (2012) Intraperitoneal chemotherapy. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 1900–1901. doi:10.1007/978-3-642-16483-5_3124Google Scholar
  10. (2012) Mucinous neoplasms. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2386. doi:10.1007/978-3-642-16483-5_3874Google Scholar
  11. (2012) Peritoneal dissemination. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2819. doi:10.1007/978-3-642-16483-5_4460Google Scholar
  12. (2012) Peritonectomy. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2819. doi:10.1007/978-3-642-16483-5_4465Google Scholar
  13. (2012) Peritoneum. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2819. doi:10.1007/978-3-642-16483-5_4467Google Scholar
  14. (2012) Peritoneum as the first line of defense. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2819. doi:10.1007/978-3-642-16483-5_4468Google Scholar
  15. (2012) Surgical debulking. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3575. doi:10.1007/978-3-642-16483-5_5598Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Washington Cancer InstituteWashington Hospital CenterWashingtonUSA