Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Mesoblastic Nephroma

  • Rhoikos Furtwängler
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_3644-2



Mesoblastic nephroma is a rare mesenchymal tumor of the kidney, which typically occurs in neonates and young infants and constitutes the most frequent renal tumor in the first 3 months of life.


Mesoblastic nephroma (MN) is a rare malignant tumor of the kidney, which originates from the mesenchymal anlage (metanephrogenic blastema). The typical patient is a neonate or young infant. In the first 3 months of life, MN is the most frequent renal tumor; hence, preoperative chemotherapy is not recommended for renal tumors in this age group. It accounts for 5 % of all childhood renal tumors. According to the German Childhood Cancer Registry, the cumulative incidence of MN is estimated at 1 in 150,000 children (0–14 years) in Germany. Contrary to nephroblastoma, MN has a 2–1...


Renal Tumor Rhabdoid Tumor Hippo Pathway Clear Cell Sarcoma Cystic Nephroma 
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See Also

  1. Clear cell sarcoma of the kidney. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 880. doi:10.1007/978-3-642-16483-5_1210Google Scholar
  2. Metanephrogenic blastema. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2259. doi:10.1007/978-3-642-16483-5_3668Google Scholar
  3. SIOP. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3413. doi:10.1007/978-3-642-16483-5_5319Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Universitätsklinikum des Saarlandes, Klinik für Pädiatrische Onkologie und HämatologieHomburg/SaarGermany