Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Koch’s Postulates

  • Roy J. Duhé
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_3242-2

Synonyms

Definition

A set of criteria used to identify the specific pathogen that causes an infectious disease.

Characteristics

Koch’s postulates are attributed to Robert Koch, who received the 1905 Nobel Prize in Medicine or Physiology “for his investigations and discoveries in relation to tuberculosis.” Jakob Henle was a professor at the University of Göttingen when Koch enrolled as a student there in 1862, and Henle was one of the early proponents of the idea that contagious diseases were caused by microorganisms. In the early days of bacteriology, there were numerous heated arguments over the identity of pathogenic agents. The presence of commensal microorganisms alongside pathogenic microorganisms often resulted in the misidentification of the real disease-causing organism. At that time, there was also a school of thought which held that there were no true bacterial species, but rather that a bacterium could adopt nearly limitless morphologies and...

Keywords

Mycobacterium Tuberculosis Chromosomal Translocation Bacillus Anthracis Pathogenic Agent Food Spoilage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. Evans AS (1976) Causation and disease: The Henle–Koch postulates revisited. Yale J Biol Med 49:175–195PubMedPubMedCentralGoogle Scholar
  2. Rivers TM (1937) Viruses and Koch’s postulates. J Bacteriol 33:1–12PubMedPubMedCentralGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Department of Pharmacology and ToxicologyUniversity of Mississippi Medical CenterJacksonUSA