Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Indirubin and Indirubin Derivatives

  • Gerhard Eisenbrand
  • Karl-Heinz Merz
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_3032-2

Synonyms

Definition

Indirubin is the parent compound of a spectrum of 2′,3-bisindoles synthesized to improve the biological activity of this natural 2′,3-bisindole lead structure. Indirubin and its isomers indigo and isoindigo are composed of two indolinone ring systems, linked through a double bond to make up 2,2′-(indigo), 3,2′-(indirubin) and 3,3′ (isoindigo) bisindoles, respectively (Fig. 1).

Keywords

Chinese Scientist Inhibit Receptor Tyrosine Kinase Kinase Inhibitory Activity Traditional Chinese Medication Natural Indigo 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Department of Chemistry, Division of Food Chemistry and ToxicologyUniversity of KaiserslauternKaiserslauternGermany