Modified version of Lokeshwar VB, Selzer MG (2012) Hyaluronidase. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, pp 1772–1775. doi: 10.1007/978-3-642-16483-5_2881
References
Benitez A, Yates TJ, Lopez LE, Cerwinka WH, Bakkar A, Lokeshwar VB (2011) Targeting hyaluronidase for cancer therapy: antitumor activity of sulfated hyaluronic acid in prostate cancer cells. Cancer Res 71(12):4085–4095. doi:10.1158/0008-5472.CAN-10-4610
Isoyama T, Thwaites D, Selzer MG, Carey RI, Barbucci R, Lokeshwar VB (2006) Differential selectivity of hyaluronidase inhibitors toward acidic and basic hyaluronidases. Glycobiology 16(1):11–21. doi:10.1093/glycob/cwj036
Lokeshwar VB, Schroeder GL, Carey RI, Soloway MS, Iida N (2002) Regulation of hyaluronidase activity by alternative mRNA splicing. J Biol Chem 277(37):33654–33663. doi:10.1074/jbc.M203821200
Lokeshwar VB, Cerwinka WH, Isoyama T, Lokeshwar BL (2005) HYAL1 hyaluronidase in prostate cancer: a tumor promoter and suppressor. Cancer Res 65(17):7782–7789. doi:10.1158/0008-5472.CAN-05-1022
Lokeshwar VB, Estrella V, Lopez L, Kramer M, Gomez P, Soloway MS, Lokeshwar BL (2006) HYAL1-v1, an alternatively spliced variant of HYAL1 hyaluronidase: a negative regulator of bladder cancer. Cancer Res 66(23):11219–11227. doi:10.1158/0008-5472.CAN-06-1121
Lokeshwar VB, Gomez P, Kramer M, Knapp J, McCornack MA, Lopez LE, Fregien N, Dhir N, Scherer S, Klumpp DJ, Manoharan M, Soloway MS, Lokeshwar BL (2008) Epigenetic regulation of HYAL-1 hyaluronidase expression. identification of HYAL-1 promoter. J Biol Chem 283(43):29215–29227. doi:10.1074/jbc.M801101200
Lokeshwar VB, Mirza S, Jordan A (2014) Targeting hyaluronic acid family for cancer chemoprevention and therapy. Adv Cancer Res 123:35–65. doi:10.1016/B978-0-12-800092-2.00002-2
McAtee CO, Barycki JJ, Simpson MA (2014) Emerging roles for hyaluronidase in cancer metastasis and therapy. Adv Cancer Res 123:1–34. doi:10.1016/B978-0-12-800092-2.00001-0
Stern R, Jedrzejas MJ (2006) Hyaluronidases: their genomics, structures, and mechanisms of action. Chem Rev 106(3):818–839. doi:10.1021/cr050247k
Yang R, Pfutze K, Zucknick M, Sutter C, Wappenschmidt B, Marme F, Qu B, Cuk K, Engel C, Schott S, Schneeweiss A, Brenner H, Claus R, Plass C, Bugert P, Hoth M, Sohn C, Schmutzler R, Bartram CR, Burwinkel B (2015) DNA methylation array analyses identified breast cancer-associated HYAL2 methylation in peripheral blood. Int J Cancer 136(8):1845–1855. doi:10.1002/ijc.29205
See Also
(2012) Biomarkers. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 408–409. doi:10.1007/978-3-642-16483-5_6601
(2012) Targeted therapy. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3610. doi:10.1007/978-3-642-16483-5_5677
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer-Verlag Berlin Heidelberg
About this entry
Cite this entry
Racine, R., Lokeshwar, V.B. (2015). Hyaluronidase. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_2881-2
Download citation
DOI: https://doi.org/10.1007/978-3-642-27841-9_2881-2
Received:
Accepted:
Published:
Publisher Name: Springer, Berlin, Heidelberg
Online ISBN: 978-3-642-27841-9
eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences