Glycobiology and Cancer
Glycobiology is a discipline of natural sciences covering studies of the structure, biosynthesis, and biology of glycans and glycoconjugates and proteins that specifically interact with these. It is involved in almost every aspect of cancer: transformation, progression, metastasis, diagnosis, monitoring, and therapy. Still, the general awareness of the potential and clinical use of discoveries in glycobiology among oncologists, or in oncology among glycobiologists, is limited.
Glycan Structural Diversity Is Theoretically Immense but Genetically Restricted
KeywordsGlycan Structure Enzymatic Glycosylation Aberrant Glycosylation Homing Process Aglycone Part
- Varki A, Cummings RD, Esko JD, Freeze HH, Stanley P, Bertozzi CR, Hart GW, Etzler ME (eds) (2009) Essentials of glycobiology, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor. Chapter 44Google Scholar