Carcinomas of the stomach are heterogeneous tumors from the morphologic standpoint. This heterogeneity is reflected in the histopathologic classifications of the tumors. The most common classifications are the Lauren classification and the World Health Organization (WHO) classification.
The Lauren classification recognizes two major types of gastric carcinomas, the “intestinal” and the “diffuse,” which display different clinicopathological characteristics and occur in different epidemiologic settings. Microscopically, the “intestinal”-type gastric carcinoma retains a glandular structure and cellular adhesion/polarity....