Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Gallbladder Cancer

  • Giorgia Randi
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_2307-3

Definition

The biliary tract consists of an interconnected system of intra- and extrahepatic ducts that transport bile secreted from the liver to the digestive tract. The gallbladder is an important organ of the biliary system lying just under the liver, receiving, storing, and then releasing the bile through bile ducts into the duodenum to help in digesting fat. Gallbladder cancer (GC) is the most common type of cancer of the biliary tract.

Characteristics

GC is a relatively rare neoplasm and despite being a non sex-related cancer is severalfold more frequent among women than among men. Detection of GC is quite difficult because symptoms and signs of GC are not specific and often appear late in the clinical course of the disease. For this reason, diagnosis is generally made when the cancer is already in advanced stages and prognosis for survival is less than 5 years in 90 % of cases.

Descriptive Epidemiology

GC incidence is characterized by a wide worldwide variation (Fig. 1) being...

Keywords

Biliary Tract Gallbladder Cancer Biliary Tract Cancer Gallbladder Disease Cholesterol Gallstone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. Lazcano-Ponce EC, Miquel JF, Munoz N et al (2001) Epidemiology and molecular pathology of gallbladder cancer. CA Cancer J Clin 51:349–364CrossRefPubMedGoogle Scholar
  2. Misra S, Chaturvedi A, Misra NC et al (2003) Carcinoma of the gallbladder. Lancet Oncol 4:167–176CrossRefPubMedGoogle Scholar
  3. Pandey M (2003) Risk factors for gallbladder cancer: a reappraisal. Eur J Cancer Prev 12:15–24CrossRefPubMedGoogle Scholar
  4. Randi G, Franceschi S, La Vecchia C (2006) Gallbladder cancer worldwide: geographical distribution and risk factors. Int J Cancer 118(7):1591–1602CrossRefPubMedGoogle Scholar
  5. Wistuba II, Gazdar AF (2004) Gallbladder cancer: lessons from a rare tumour. Nat Rev Cancer 4:695–706CrossRefPubMedGoogle Scholar

See Also

  1. (2012) Bile. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 397. doi: 10.1007/978-3-642-16483-5_614Google Scholar
  2. (2012) Cholecystectomy. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, pp 820-821. doi:10.1007/978-3-642-16483-5_1111Google Scholar
  3. (2012) Cholecystitis. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 821. doi:10.1007/978-3-642-16483-5_1112Google Scholar
  4. (2012) Epidemiologic studies. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 1269. doi: 10.1007/978-3-642-16483-5_1929Google Scholar
  5. (2012) Gallstones. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 1493. doi:10.1007/978-3-642-16483-5_2308Google Scholar
  6. (2012) Incidence rate. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 1839. doi:10.1007/978-3-642-16483-5_3029Google Scholar
  7. (2012) Obesity. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 2595. doi:10.1007/978-3-642-16483-5_4185Google Scholar
  8. (2012) Risk factor. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 3310. doi:10.1007/978-3-642-16483-5_5111Google Scholar
  9. (2012) Salmonella typhi and paratyphi. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, pp 3331-3332. doi:10.1007/978-3-642-16483-5_5151Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of EpidemiologyInstitute for Farmacological Research Mario NegriMilanItaly