Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Follicular Thyroid Tumors

  • Jean-Michel Bidart
  • Martin Schlumberger
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_2241-2

Synonyms

Definition

Are tumors derived from the thyrocyte, the cellular unit of thyroid follicle. These tumors include benign adenomas, papillary and follicular carcinomas, two entities considered as differentiated carcinomas, and undifferentiated or anaplastic carcinomas.

Characteristics

Clinical thyroid nodules, which are the consequence of abnormal localized growth of the thyroid tissue, are detected in 4–7 % of the general population in an iodine sufficient area. The prevalence is higher in countries affected by moderate or severe iodine deficiency. Infraclinical nodules are even more common, depending on the techniques used for screening, and ultrasonography detects nodules in more than 50 % of women older than 60 years. About 5 % of thyroid nodules are malignant. The annual incidence of thyroid carcinoma, the most common malignancies of endocrine organs, ranges...

Keywords

Thyroid Carcinoma Papillary Thyroid Carcinoma Thyroid Nodule Papillary Carcinoma Iodine Deficiency 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. Cooper DS, Doherty GM, Haugen BR et al (2006) The American Thyroid Association Guidelines Taskforce Management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 16:109–142CrossRefPubMedGoogle Scholar
  2. DeLellis RA, Lloyd RV, Heitz PU et al (2004) Pathology and genetics: tumours of endocrine organs, World Health Organization classification of tumours. IARC Press, LyonGoogle Scholar
  3. Kondo T, Ezzat S, Asa SL (2006) Pathogenic mechanisms in thyroid follicular-cell neoplasia. Nat Rev Cancer 6:292–306CrossRefPubMedGoogle Scholar
  4. Schlumberger M, Pacini F (2003) Thyroid tumors, 2nd edn. Editions Nucléon, ParisGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of Clinical BiologyInstitut Gustave-RoussyVillejuifFrance
  2. 2.Department of Nuclear Medicine and Endocrine Oncology, Referral Center for Refractory Thyroid TumorsInstitut National du Cancer, Institut Gustave RoussyVillejuifFrance