Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Exfoliation of Cells

  • Alexandre Loktionov
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_2056-2

Synonyms

Definition

Cell exfoliation (Latin – exfoliare – to strip of leaves) is a process of spontaneous or induced complete detachment of single epithelial cells or groups of cells from an epithelial layer.

Characteristics

Exfoliation of cells is one of the main mechanisms of cell loss participating in the homeostatic control of cell population size. Cell exfoliation is a characteristic feature of epithelial tissues forming epithelial layers covering both external body surface (skin epidermis and skin appendages) and surfaces of internal cavities and passages (gastrointestinal tract, respiratory system, and genitourinary system) as well as major exocrine glands and glandular ducts (mammary gland, exocrine pancreas, biliary system, etc.). Cell exfoliation process in normal physiological conditions is closely associated with terminal differentiation and orderly loss of dying cells compensated by permanent cell population renewal. This relationship...

Keywords

Focal Adhesion Kinase Adherens Junction Prostate Epithelium Cervical Smear Buccal Mucosal Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

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See Also

  1. (2012) Biopsy. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 415. doi:10.1007/978-3-642-16483-5_644Google Scholar
  2. (2012) Cilia. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 857. doi:10.1007/978-3-642-16483-5_1168Google Scholar
  3. (2012) Focal adhesion. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 1436–1437. doi:10.1007/978-3-642-16483-5_2227Google Scholar
  4. (2012) Mucocellular layer. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2389. doi:10.1007/978-3-642-16483-5_3877Google Scholar
  5. (2012) Multi-marker panels. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2394. doi:10.1007/978-3-642-16483-5_3884Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.DiagNodus LtdBabraham Research CampusCambridgeUK