Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Epigallocatechin

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_1937-3

Synonyms

Definition

Epigallocatechin is one of the several biologically active ingredients that make up the bulk of the potent antioxidant polyphenols known as catechins, which are found in green tea Green Tea Cancer Prevention.

Characteristics

Next to water, tea is the second most widely consumed beverage in the world. Green tea, like oolong and black teas, is derived from the Camellia sinensis plant, but is processed immediately from fresh leaves and is protected from oxidation. The biologically active ingredients in green tea are a family of polyphenols (catechins) and flavonols, which are very strong antioxidants. The catechins comprise about 90 % of the bulk of green tea and include epicatechin (EC), epigallocatechin (EGC), epicatechin gallate (ECG), and epigallocatechin gallate (EGCG) (Fig. 1). The catechins are characterized by the presence of a di- or trihydroxyl group substitution on the “B”-ring and the meta-5.7-dihydroxyl substitution at the...

Keywords

Chemopreventive Agent Epigallocatechin Gallate Epicatechin Gallate Cancer Cell Adhesion Epidermal Growth Factor Family 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

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  2. Bode AM, Dong Z (2006) Molecular and cellular targets. Mol Carcinog 45:422–430PubMedCentralCrossRefPubMedGoogle Scholar
  3. Na HK, Surh YJ (2006) Intracellular signaling network as a prime chemopreventive target of (−)-epigallocatechin gallate. Mol Nutr Food Res 50:152–159CrossRefPubMedGoogle Scholar
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See Also

  1. (2012) AKT. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 115. doi:10.1007/978-3-642-16483-5_163Google Scholar
  2. (2012) Laminin. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 1971–1972. doi:10.1007/978-3-642-16483-5_3268Google Scholar
  3. (2012) Senescence. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3370. doi:10.1007/978-3-642-16483-5_5236Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.The Hormel Institute, University of MinnesotaAustinUSA