Living reference work entry
Epithelial cell-cell junctions consist of four junctions: tight junctions, adherens junctions, desmosomes, and gap junctions (Fig. 1). Two adhering-type junctions, the adherens junctions and the desmosomes, are responsible for strong cell-cell adhesion. Each of these junctions consists of a transmembrane cadherin and a complex cytoplasmic plaque that serve to link cadherin to actin microfilaments or the intermediate filament cytoskeleton.
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