Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab


  • Manfred Schwab
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_1431-2


Cyclins are a family of proteins involved in the cell cycle progression, cooperating with its catalytic partner cyclin-dependent kinase (CDK), which activates the protein kinase function. The most important substrate of cyclin/CDK complex is retinoblastoma protein (Rb).



Cell Cycle Protein Kinase Cancer Research Cycle Progression Cell Cycle Progression 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.German Cancer Research Center (DKFZ)HeidelbergGermany