Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Cyclins

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_1431-2

Definition

Cyclins are a family of proteins involved in the cell cycle progression, cooperating with its catalytic partner cyclin-dependent kinase (CDK), which activates the protein kinase function. The most important substrate of cyclin/CDK complex is retinoblastoma protein (Rb).

Cross-References

Keywords

Cell Cycle Protein Kinase Cancer Research Cycle Progression Cell Cycle Progression 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.German Cancer Research Center (DKFZ)HeidelbergGermany