Definition
Crohn’s disease (also: regional enteritis) and ulcerative colitis area chronic, inflammatory conditions of the gastrointestinal tract. Although the inflammation of the mucosa is usually episodic in nature, these Inflammatory bowel diseases (IBD) are associated with an increased risk of developing colorectal cancer. Inflammatory bowel disease well-managed patients suffering from IBD have an approximately two times higher chance for contracting CRC as the population at large.
Characteristics
Inflammatory bowel disease (IBD) patients, which include the two related conditions of Crohn’s disease and ulcerative colitis, have an increased risk of developing colorectal cancer (CRC) (Itzkowitz and Yio 2004). For patients with Crohn’s disease [CD], the excess risk for contracting CRC has been estimated at 1.9, whereas the risk for small bowel cancer is 27.1...
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References
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Dijkstra, G., Peppelenbosch, M.P. (2015). Crohn Disease. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_1379-2
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DOI: https://doi.org/10.1007/978-3-642-27841-9_1379-2
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