Contralateral Breast Cancer
Bilateral primary breast cancer: increasing breast cancer incidence rates, improved prognosis, and growing life expectancy have resulted in an increasing number of women at risk of developing bilateral primary breast cancer. In the USA alone, there are approximately 2.2 million living diagnosed at sometime with breast cancer.
Contralateral breast cancers are divided in those that are synchronous, that is, when breast cancers are diagnosed in both breasts simultaneously, and metachronous, normally defined as diagnosed more than 6 months from the first cancer. The age-specific incidence of synchronous breast cancer mimics that of unilateral breast cancer. In contrast, the risk of being diagnosed with a metachronous bilateral cancer is higher among women diagnosed before the age of 45 compared to those older at time of diagnoses of the first breast cancer. The risk of metachronous bilateral breast cancer is elevated throughout the entire life of a woman and is approximately...