Adult T-Cell Leukemia
A leukemia of mature T lymphocytes (T cells) developing in adults, resulting from infection with the human T-cell leukemia virus (HTLV) and characterized by circulating malignant T lymphocytes, skin lesions, lymphadenopathy (enlarged lymph nodes), hepatosplenomegaly (enlarged liver and spleen), hypercalcemia (high blood calcium), lytic (“punched out”) bone lesions, and a tendency to infection. There are four categories of ATL, based on the aggressiveness of the disease – smoldering, chronic, lymphoma, and acute.
KeywordsLymph Node Cancer Research Skin Lesion Bone Lesion Leukemia Virus
- (2012) T cell. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3599. doi: 10.1007/978-3-642-16483-5_5645Google Scholar