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Adipose Tumors

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Encyclopedia of Cancer

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Synonyms

Adipocytic tumors; Lipomas; Lipomatous tumors; Liposarcomas

Definition

Adipose tumors (AT) are mesenchymal neoplasms that form the largest group of human tumors. They include benign tumors, such as the very common lipomas, as well as rare malignant tumors with various degrees of clinical aggressiveness. Histologically, AT consist of adipocytic cells showing different levels of differentiation, from mature adipocytes in benign lipomas up to undifferentiated lipoblastic cells in high-grade liposarcomas. The 2002 World Health Organization classification distinguishes seven entities of benign AT: lipoma, lipoblastoma/lipoblastomatosis, angiolipoma, myolipoma of soft tissue, chondroid lipoma, spindle cell/pleomorphic lipoma, and hibernoma. Malignant AT, also called liposarcomas, include three types: well-differentiated liposarcoma/dedifferentiated liposarcoma, myxoid/round cell liposarcoma, and pleomorphic liposarcoma. Except for the ordinary superficial lipomas, differential...

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References

  • Fletcher C, Unni K, Mertens F (eds) (2002) World Health Organization classification of tumours pathology and genetics of tumours of soft tissue and bone. IARC Press, Lyon

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  • Sandberg AA (2004a) Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: liposarcoma. Cancer Genet Cytogenet 155:1–24

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See Also

  • (2012) Chromosome. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 848. doi:10.1007/978-3-642-16483-5_1145

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  • (2012) Dedifferentiation. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1072. doi:10.1007/978-3-642-16483-5_1547

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  • (2012) High Content Screen. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1694. doi:10.1007/978-3-642-16483-5_2721

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  • (2012) Lipoma. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2056. doi:10.1007/978-3-642-16483-5_3379

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  • (2012) Neocentromere. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2473. doi:10.1007/978-3-642-16483-5_4009

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  • (2012) Point Mutation. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2934. doi:10.1007/978-3-642-16483-5_4653

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Author information

Authors and Affiliations

  1. Laboratory of Solid Tumors Genetics, Faculty of Medicine, Nice University Hospital, CNRS UMR 6543, Nice, France

    Florence Pedeutour

  2. Early Phase Trials and Sarcoma Units, Institut Bergonie, Bordeaux, France

    Antoine Italiano

Authors
  1. Florence Pedeutour
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  2. Antoine Italiano
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Corresponding author

Correspondence to Florence Pedeutour .

Editor information

Editors and Affiliations

  1. Abt. Tumorgenetik, Deutsches Krebsforschungszentrum, Heidelberg, Germany

    Manfred Schwab

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Pedeutour, F., Italiano, A. (2015). Adipose Tumors. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_106-2

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  • DOI: https://doi.org/10.1007/978-3-642-27841-9_106-2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27841-9

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