Encyclopedia of Astrobiology

Living Edition
| Editors: Muriel Gargaud, William M. Irvine, Ricardo Amils, Henderson James Cleaves, Daniele Pinti, José Cernicharo Quintanilla, Michel Viso


  • Juli Peretó
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27833-4_653-2



Gluconeogenesis refers to the biosynthetic pathway of hexoses from noncarbohydrate substrates such as acetate, glycerol, pyruvate, etc. This can be achieved by conversion of the precursor into an intermediate of glycolysis and the reverse of this pathway (with the appropriate bypass of three irreversible enzymatic steps). The phylogenetic distribution of the gluconeogenetic enzymes suggests an early origin of this anabolic pathway, before the emergence of the different glycolytic pathways.

See Also


Bioorganic Chemistry Biosynthetic Pathway Glycolytic Pathway Enzymatic Step Phylogenetic Distribution 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Institut Cavanilles de Biodiversitat i Biologia EvolutivaUniversitat de ValènciaValènciaSpain