Encyclopedia of Astrobiology

Living Edition
| Editors: Muriel Gargaud, William M. Irvine, Ricardo Amils, Henderson James Cleaves, Daniele Pinti, José Cernicharo Quintanilla, Michel Viso


  • Henderson James (Jim) CleavesIIEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27833-4_603-3



FRET is a technique used to measure the proximity of chemical groups in macromolecules or between host and guest molecules. It involves the use of a donor (in an excited electronic state) and acceptor chromophore. When they are in close proximity (usually <10 nm), the donor may transfer its energy to the acceptor through nonradiative dipole-dipole coupling. This is known as “Förster resonance energy transfer.” When both chromophores are fluorescent, the term “fluorescence resonance energy transfer” is used instead, although the energy is not actually transferred by fluorescence but by nonradiative transfer.

See Also


Energy Transfer Electronic State Bioorganic Chemistry Fluorescence Resonance Energy Transfer Resonance Energy 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Geophysical LaboratoryCarnegie Institution of WashingtonWashingtonUSA