Definition
A proteome is the complete set of proteins encoded by a genome. It is also defined as the proteincomplement of the genome. Whereas the proteome of a species is the whole set of potentially expressed proteins, the proteome of an individual organism displays variations according to the cell cycle, metabolic status, and environment-dependent variables. In multicellular organisms, the proteome is the subset of all encoded proteins which is expressed in a cell or tissue, also affected by the developmental stage and health of the organism. Proteomics is the field of molecular biology which studies the entire proteome for determining the structures and functions of the expressed proteins, as well as the relationships among them. Technologies widely used in proteomics include two-dimensional gel electrophoresis, mass spectrometry, techniques for structural characterization of proteins, and proteome-focused bioinformatic tools. In parallel to proteomics, other global and...
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© 2014 Springer-Verlag Berlin Heidelberg
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Briones, C. (2014). Proteome, Proteomics. In: Amils, R., et al. Encyclopedia of Astrobiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27833-4_1289-3
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DOI: https://doi.org/10.1007/978-3-642-27833-4_1289-3
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Publisher Name: Springer, Berlin, Heidelberg
Online ISBN: 978-3-642-27833-4
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