Malaria: Differential Blood Counts
During the last years, blood counts came in the scope of prognostics for infectious diseases such as malaria. The ratio of neutrophil-to-lymphocyte count (NLCR) was proposed as prognostic factor for clinical outcome of malaria and as parameter of systemic inflammation and stress. It was shown that NLCR correlated with parasitemia. Lymphocytopenia and high NLCR are considered as significant predictors of sepsis. Thrombocytopenia and anemia are typical characteristics during and following an infection with Plasmodium stages, while leucocytes turned out to be rather stable during such an infection. In addition NLCR and lymphocytopenia were shown to be significant markers for treatment outcome of severe malaria.