Encyclopedia of Parasitology

Living Edition
| Editors: Heinz Mehlhorn

Acylation

  • Heinz Mehlhorn
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27769-6_4911-1

The addition of fatty acid moieties such as myristate and palmitate is essential for the growth and pertaining of infectivity of trypanosomatids such as members of the genera Trypanosoma and Leishmania. These trypanosomatids possess a single N-myristoyltransferase (NMT) and several (multiple) palmitoyl acyltransferases. Blocking of these transferases would be a means to control trypanosomiasis.

Keywords

Acid Moiety Fatty Acid Moiety Palmitoyl Acyltransferases 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Further Reading

  1. Goldston AM et al (2014) Acylation in trypanosomatids: an essential process and potential drug target. Trends Parasitol 30:350–360CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Institut für Zoomorphologie, Zellbiologie und ParasitologieHeinrich-Heine-UniversitätDüsseldorfGermany