Encyclopedia of Parasitology

Living Edition
| Editors: Heinz Mehlhorn

Schistosoma Species Protein Kinases

  • Heinz Mehlhorn
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27769-6_4885-1

Recently it was shown that protein kinases (PKs) control important biological processes in schistosomes as well as that other PKs are involved in the etiology of cancer. This led to the development of several anticancer drugs that inhibit deregulated PKs. Thus there are approaches to use these PKs-blockers as tentative new antischistosomal medicaments in future, if praziquantel should loose its activity against schistosomes.


Protein Kinase Biological Process Anticancer Drug Species Protein Important Biological Process 
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Further Reading

  1. Dissous C, Grevelding CG (2011) Piggy-backing the concept of cancer drugs for schistosomiasis treatment: a tangible perspective. Trends Parasitol 27:59–66CrossRefPubMedGoogle Scholar
  2. Knobloch J et al (2006) Herbimycin A suppresses mitotic activity and egg production of female Schistosoma mansoni. Int J Parasitol 36:1261–1272CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Institut für Zoomorphologie, Zellbiologie und ParasitologieHeinrich-Heine-UniversitätDüsseldorfGermany