Skip to main content
SpringerLink
Log in
Book cover

Encyclopedia of Parasitology pp 1Cite as

Myotubes

  • Living reference work entry
  • First Online:

  • 303 Accesses

This term describes fully developed muscle fibers, where bradyzoite-containing Toxoplasma gondii cysts are developed after invasion of tachyzoites. This development was correlated with the up-regulation of the negative cell cycle regulators

  1. 1.

    testis-specific Y-encoded-like protein 2 (Tspyl2) and

  2. 2.

    p21 (waf1Cip1)

as well as is connected with the down-regulation of the cell cycle activator cyclin B1 and with absence of DNA synthesis. Following a penetration of tachyzoites of T. gondii, myotubes (but not their progenitors: myoblasts or fibroblasts) further upregulate Tspyl2.

This is a preview of subscription content, log in via an institution.

Author information

Authors and Affiliations

  1. Institut für Zoomorphologie, Zellbiologie und Parasitologie, Heinrich-Heine-Universität, Universitätsstraße 1, 40225, Düsseldorf, Germany

    Heinz Mehlhorn

Authors
  1. Heinz Mehlhorn
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Heinz Mehlhorn .

Editor information

Editors and Affiliations

  1. Institute of Zoomorphology and Parasitology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

    Heinz Mehlhorn

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Mehlhorn, H. (2015). Myotubes. In: Mehlhorn, H. (eds) Encyclopedia of Parasitology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27769-6_4766-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-27769-6_4766-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27769-6

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

Publish with us

Policies and ethics

Search

Navigation