Encyclopedia of Parasitology

Living Edition
| Editors: Heinz Mehlhorn

VSAs

  • Heinz Mehlhorn
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27769-6_4396-1

This term represents the abbreviation for “variable surface antigens,” which are produced by the parasite and found on the surface of, e.g., parasitized erythrocytes (in the case of Plasmodium infections). These VSAs promote the adhesion of infected erythrocytes to endothelium cells of the host and also act antigenetically to the host immune system. In order to mitigate host immune defense, the malarial parasites (and others) have evolved from a variety of VSA genes.

Keywords

Endothelium Cell Immune System Surface Antigen Immune Defense Host Immune System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Institut für Zoomorphologie, Zellbiologie und ParasitologieHeinrich-Heine-UniversitätDüsseldorfGermany