Greek: kholera; English: drip = flow of bile; Hebrew: chaul rah = bad disease.
This disease due to the gram-negative bacterium Vibrio cholerae (0.5 μm × 1.5–3 μm) has main symptoms such as watery diarrhea, vomiting, and severe dehydration, which may lead to death (due to shock reaction) or may stay on the level of common, not life-threatening diarrheas. Therefore, it is needed to initiate differential examinations, if infections with parasites (e.g., Entamoeba histolytica, Cyclospora, or Isospora) are supposed. Among the 200 serotypes of Vibrio cholera, which possess the main surface antigen O, only two (O1 and O139) lead to the endemic and epidemic cholera. The recent seventh cholera pandemic is different from the preceding ones by the fact that it is not based on the classic Vibrio but on the biotype El Tor (named according to the quarantine station on the Sinai peninsula, where this type was isolated first in 1905).
KeywordsSurface Antigen Main Symptom Watery Diarrhea Pasteur Institute Entamoeba Histolytica
- Grüntzig J, Mehlhorn H (2010) Expeditions into the Empire of Plagues. Düsseldorf University Press, DüsseldorfGoogle Scholar