Encyclopedia of Parasitology

Living Edition
| Editors: Heinz Mehlhorn

Malaria: Coinfections

  • Heinz Mehlhorn
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27769-6_4044-1

Malaria and non-typhoid Salmonella infections occur at a prominent level in sub-Saharan Africa and cause severe and often fatal illness especially in children. Recent studies have shown that iron deficiency is the important link between both diseases, since increased iron in macrophages supports survival of Salmonella spp. inside and thus leads to propagation of this disease. Thus, it has to be feared that iron supplementation programs in these regions (helping suppression of malaria effects) will help to spread non-typhoid Salmonella infections.

Further Reading

  1. van Santen S et al (2013) The iron link between malaria and invasive non typhoid Salmonella infections. Trends Parasitol 29:220–227CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Institut für Zoomorphologie, Zellbiologie und Parasitologie Universitätsstraße 1DüsseldorfGermany