Encyclopedia of Parasitology

Living Edition
| Editors: Heinz Mehlhorn

Apicoplast Genomes

  • Heinz Mehlhorn
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27769-6_3514-1
Recent studies offer deeper insights into the genomes of apicomplexan parasites. It was shown that Leucocytozoon cauleryi and Plasmodium falciparum are rather similar. They contain DNA of 85.1 % AS + T and a unit of 34,779 bp encoding almost the same set of genes including 16 + RNA and 30 protein coding genes. Only one open reading frame (ORF91) is absent in L. caulleryi. Both species contain in their apicoplast DNA two sets of a unique inverted repeat (IR) or 5,253 bp and encoding genes specifying one large and one small rRNA subunit and 9 + RNAs but no protein and separated by a unique 13 bp sequence. The phylogeny of the apicoplast genomes is depicted in Fig. 1 (Imura et al. 2014).


Code Gene Protein Code Gene Plasmodium Falciparum Protein Code Deep Insight 
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  1. Imura T et al (2014) The apicoplast genome of Leucocytozoon caulleryi, a pathogenic apicomplexan parasite of the chicken. Parasitol Res 113:823–828CrossRefPubMedGoogle Scholar

Further Reading

  1. Arisue N et al (2012) The Plasmodium apicoplast genome: conserved structure and close relationship of P. ovale to rodent malaria parasites. Mol Biol Evol 29:2095–2099CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Institut für Zoomorphologie, Zellbiologie und ParasitologieHeinrich-Heine-UniversitätDüsseldorfGermany