Definition
Microfluidic assembly refers to the realization of devices and systems for handling and analyzing microliter or nanoliter amounts of fluid through the combination of smaller subunits, including the combining of discrete microfluidic devices and components to realize complex microfluidic instrumentation. Microfluidic assembly uses various integrated and modular packaging and interfacing techniques to combine microfluidic subunits together, including bonding, mechanical press fits, robotic manipulation, and self-assembly.
Overview
Microfluidic components and systems are utilized whenever the manipulation of microliter or (usually) nanoliter amounts of fluid is beneficial or where small size for fluidic systems is needed. Examples of microfluidic applications include the miniaturization of laboratory instrumentation for bedside rapid diagnosis of...
References
Velten T, Ruf HH, Barrow D, Aspragathos N, Lazarou P, Jung E, Malek CK, Richter M, Kruckow J, Wackerle M (2005) Packaging of bio-MEMS: strategies, technologies, and applications. IEEE Trans Adv Packag 28(3):533–546
Gray BL, Jaeggi D, Mourlas NJ, van Drieuizen BP, Williams KR, Maluf NI, Kovacs GTA (1999) Novel interconnection technologies for integrated microfluidic systems. Sens Actuators A77(1):57–65
Böhringer KF, Fearing RS, Goldberg K (1998) Microassembly. In: Nof S (ed) The handbook of industrial robotics, 2nd edn. Wiley, New York, p 1045
Jo BH, van Lerberghe LM, Motsegood KM, Beebe DJ (2000) Three-dimensional micro-channel fabrication in polydimethylsiloxane (PDMS) elastomer. J Microelectromech Syst 9(1):76–81
Verpoorte EMJ, van der Schoot BH, Jeanneret S, Manz A, Widmer HM, de Rooij NF (1994) Three-dimensional micro flow manifolds for miniaturized chemical analysis systems. J Micromech Microeng 4:246–256
Krulevitch P, Benett W, Hamilton J, Maghribi M, Rose K (2002) Polymer-based packaging platform for hybrid microfluidic systems. Biomed Microdevices 4:301–308
Young IT, Moerman van den Doel RLR, Iordanov V, Kroon A, Dietrich HRC, van Dedem GWK, Bossche A, Gray BL, Sarro L, Verbeek PW, van Vliet LJ (2003) Monitoring enzymatic reactions in nanolitre wells. J Microsc 212(2):254–263
Gonzalez C, Collins SD, Smith RL (1998) Fluidic interconnects for modular assembly of chemical micro systems. Sens Actuators B 49:40–45
Gray BL, Collins SD, Smith RL (2004) Interlocking mechanical and fluidic interconnections for microfluidic circuit boards. Sens Actuators A 112:18–24
Jaffer S, Gray BL (2007) Mechanically assembled polymer interconnects with dead volume analysis for microfluidic systems. Proc SPIE Microfluid BioMEMS Med Microsyst 6465:1–12
Morrissey A, Kelly J, Alderman J (1997) 3D packaging of a microfluidic system with sensory applications. Proc SPIE 3224:161–168
Moss ED, Han A, Frazier AB (2007) A fabrication technology for multi-layer polymer-based microsystems with integrated fluidic and electrical functionality. Sens Actuators B 121:689–697
Nguyen NT, Wereley ST (2002) Chapter 3: Fabrication techniques for microfluidics, Section 3.5.2 Device level packaging. In: Nguyen NT, Wereley ST (eds) Fundamentals and applications of microfluidics. Artech House, Boston, pp 124–127
Nguyen NT, Wereley ST (2002) Chapter 6: Microfluidics for internal control: microvalves, microfluidics for internal control: micropumps. In: Nguyen NT, Wereley ST (eds) Fundamentals and applications of microfluidics. Artech House, Boston, pp 247–337
Zhou Y, Nelson B, Vikramaditya B (1998) Fusing force and vision feedback for micromanipulation. Proc Int Conf Robot Autom 2:1220–1225
Wörn H, Seyfried J, Fahlbusch S, Bürkle A (2000) Flexible microrobots for micro assembly tasks. Proc Int Symp Micromech Hum Sci 27:22–25
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer Science+Business Media New York
About this entry
Cite this entry
Gray, B. (2014). Microfluidic Assembly. In: Li, D. (eds) Encyclopedia of Microfluidics and Nanofluidics. Springer, Boston, MA. https://doi.org/10.1007/978-3-642-27758-0_926-2
Download citation
DOI: https://doi.org/10.1007/978-3-642-27758-0_926-2
Received:
Accepted:
Published:
Publisher Name: Springer, Boston, MA
Online ISBN: 978-3-642-27758-0
eBook Packages: Springer Reference EngineeringReference Module Computer Science and Engineering