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Biomolecular Synthesis in Microfluids

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Encyclopedia of Microfluidics and Nanofluidics
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Microfluidic reactor for biomolecular synthesis; Microreactor for synthesis of biomolecules; Synthesis of biological molecules in microfluidics


Biological molecules, such as proteins and peptides, oligosaccharides, nucleic acids, lipids, and their related compounds, are widely used for biomaterial and pharmaceutical applications. These compounds are expensive, not so stable for long-term storage, and do not require extremely large-scale synthesis. Also, the use of hazardous compounds is required in many cases. Therefore, the microreaction process is considered as a new approach which can overcome these restrictions in the synthesis of biomolecules. Several organic and biochemical syntheses have been performed using the microfluidic platform.


Biomolecules, fine chemicals, and pharmaceuticals are high-value products that are produced in modest quantities. They are usually seasonal products that are customer specific and have a short shelf life. These...

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Correspondence to Masaya Miyazaki .

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© 2014 Springer Science+Business Media New York

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Miyazaki, M., Maeda, H. (2014). Biomolecular Synthesis in Microfluids. In: Li, D. (eds) Encyclopedia of Microfluidics and Nanofluidics. Springer, Boston, MA.

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  • Publisher Name: Springer, Boston, MA

  • Online ISBN: 978-3-642-27758-0

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