Definition
Lab-on-Chip devices refer to devices that integrate one or several biochemical analysis functions on a chip of small size using semiconductor manufacturing processes and are capable of handling extremely small volume of fluid. They usually have the size of only square millimeters to a few square centimeters and are able to handle fluid volumes down to picoliter levels.
Lab-on-Chip devices for separation-based detection refer to Lab-on-Chip devices that are capable of performing detection based on the result of separation. Both separation and detection functionalities should be integrated in a single chip.
Overview
The history of Lab-on-Chip devices can be dated back to 1975, when the first Lab-on-Chip device, a gas chromatograph used to separate a mixture of various gases, was invented [1]. However, the real boost and serious growth in Lab-on-Chip devices were not seen until 1990 when the...
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Yeow, J.T.W., Wan, W. (2014). Lab-on-Chip Devices for Separation-Based Detection. In: Li, D. (eds) Encyclopedia of Microfluidics and Nanofluidics. Springer, Boston, MA. https://doi.org/10.1007/978-3-642-27758-0_779-3
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DOI: https://doi.org/10.1007/978-3-642-27758-0_779-3
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Publisher Name: Springer, Boston, MA
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