Definition
Electrokinetic or pressure-driven liquid flow in microchannels with three-dimensional (3D) surface roughness generated by manufacturing techniques or by adhesion of biological particles from the liquid.
Overview
Fundamental understanding of liquid flow through microchannels is important to the design and operation of lab-on-a-chip devices. The microchannel surfaces may exhibit certain degrees of roughness generated by the manufacturing techniques or by adhesion of biological particles from the liquids. The reported surface roughness elements range from 0.1 to 2 μm [1–3]. Microfabrication techniques such as photolithography can also make 3D elements inside microchannels (see Fig. 1). The surface roughness of microchannels not only increases the reaction-sensing surface area but also plays an important role in determining the flow characteristics. In early experimental...
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References
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© 2014 Springer Science+Business Media New York
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Wu, Z., Li, D. (2014). Flow in Channels with 3D Elements. In: Li, D. (eds) Encyclopedia of Microfluidics and Nanofluidics. Springer, Boston, MA. https://doi.org/10.1007/978-3-642-27758-0_543-2
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DOI: https://doi.org/10.1007/978-3-642-27758-0_543-2
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Publisher Name: Springer, Boston, MA
Online ISBN: 978-3-642-27758-0
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