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Microscale Acoustofluidics

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Encyclopedia of Microfluidics and Nanofluidics


Acoustic separation; Acoustophoresis; Position manipulation of particles by ultrasonic fields; Ultrasonic particle separation


Microscale acoustofluidics defines the use of ultrasonic waves onto a fluid inside a microchannel. The acoustic waves are imposed on the fluid through excitation of the microchannel walls with an actuator. Acoustofluidics in microchannels is commonly used for moving and manipulating microparticles in a microchannel.


Separation of cells has several applications in medicine. In apheresis applications, certain types of cells in blood are separated from the remaining cells such as in leukapheresis, plateletpheresis, erythrocytapheresis, and plasmapheresis. The general methods used for separation of cell types are filtration which relies on separation due to size differences and the use of centrifugation which is separation through density differences. In order to prevent clogging of the filter, the filter is rinsed with a fluid flowing...

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Correspondence to Barbaros Cetin .

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Cetin, B., Buyukkocak, S., Özer, M.B. (2013). Microscale Acoustofluidics. In: Li, D. (eds) Encyclopedia of Microfluidics and Nanofluidics. Springer, Boston, MA.

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