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Drug Discovery and Evaluation: Pharmacological Assays pp 1–6Cite as

Antipyretic Activity

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Abstract

Treatment with antipyretics has been very important in the pre-antibiotic era. Nevertheless, for treatment of acute viral diseases and for treatment of protozoal infections like malaria, the reduction of elevated body temperature by antipyretics is still necessary. For anti-inflammatory compounds, an antipyretic activity is regarded as a positive side effect. To evaluate these properties, fever is induced in rabbits or rats by injection of lipopolysaccharides or brewer’s yeast.

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Authors and Affiliations

  1. Pfizer Inc, New Jersey, USA

    Vino Daniel

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  1. Vino Daniel
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Correspondence to Vino Daniel .

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Editors and Affiliations

  1. Dieburg, Germany

    Franz J. Hock

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© 2014 Springer-Verlag Berlin Heidelberg

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Daniel, V. (2014). Antipyretic Activity. In: Hock, F. (eds) Drug Discovery and Evaluation: Pharmacological Assays. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27728-3_43-1

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  • DOI: https://doi.org/10.1007/978-3-642-27728-3_43-1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27728-3

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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