Antipyretic Activity

  • Vino Daniel
Living reference work entry


Treatment with antipyretics has been very important in the pre-antibiotic era. Nevertheless, for treatment of acute viral diseases and for treatment of protozoal infections like malaria, the reduction of elevated body temperature by antipyretics is still necessary. For anti-inflammatory compounds, an antipyretic activity is regarded as a positive side effect. To evaluate these properties, fever is induced in rabbits or rats by injection of lipopolysaccharides or brewer’s yeast.


Antipyretic Effect Elevated Body Temperature Antipyretic Drug Organum Vasculosum Lamina Terminalis Record Body Temperature 
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References and Further Reading

General Considerations

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Antipyretic Testing in Rabbits

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Pfizer IncNew JerseyUSA

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