Impaired Renal Function

  • Susan Emeigh Hart
Living reference work entry


Chronic renal failure is a frequent pathological condition in man. An animal model as described by Acott et al. (1987) is of value to test new diuretics under these conditions.


Chronic Renal Failure Autosomal Dominant Polycystic Kidney Disease Candesartan Cilexetil Unilateral Ureteral Obstruction Puromycin Aminonucleoside 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References and Further Reading

Chronic Renal Failure in the Rat

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Chronic Renal Failure After Subtotal (Five-Sixths) Nephrectomy in Rats

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Experimental Nephritis

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Nephrotoxic Serum Nephritis

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Experimental Nephrosis

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  18. Pedraza-Chaverri J, Granados-Silvestre MA, Medina-Campos ON, Hernández-Pando R (1999) Effect of the in vivo catalase inhibition on aminonucleoside nephrosis. Free Radic Biol Med 27:245–253CrossRefPubMedGoogle Scholar
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  20. Yayama K, Kawao M, Tujii H, Itoh N, Okamoto H (1993) Dup 753 prevents the development of puromycin aminonucleoside-induced nephrosis. Eur J Pharmacol 236:337–338CrossRefPubMedGoogle Scholar
  21. Yoneda H, Toriumi W, Ohmachi Y, Okumura F, Fujimura H, Nishiyama S (1998) Involvement of angiotensin II in development of spontaneous nephrosis in Dahl salt-sensitive rats. Eur J Pharmacol 362:213–219CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Non-Clinical Drug SafetyBoehringer Ingelheim Pharmaceuticals, IncRidgefieldUSA

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