Techniques to characterize the barrier function of the skin include a number of noninvasive methods to measure moisture content and loss through the skin surface. One of these measurements is the determination of skin hydration using a method known as corneometry (Bilchmann and Serup 1988). This technique determines the capacitance of the skin due to its behavior as a dielectric medium and assesses a 10–20-μm thickness of the stratum corneum. The method has been compared with other techniques (Van Neste 1991; Fluhr et al. 2001) and applied to evaluate dermatological and cosmetic products in human volunteers (Zuang et al. 1997; Singh et al. 2001; Yilmaz and Borchert 2006).
KeywordsStratum Corneum Barrier Function Skin Surface Human Volunteer Noninvasive Method
References and Further Reading
- Bilchmann CW, Serup J (1988) Assessment of skin moisture. Measurement of electric conductance, capacitance and transepidermal water loss. Acta Derm Venereol 68:284–290Google Scholar
- Zuang V, Rona C, Distante F, Barardesca E (1997) The use of a capacitance device to evaluate the hydration of human skin. J Appl Cosmetol 15:95–102Google Scholar