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Abstract

Developmental and reproductive toxicity is a special part of toxicology which comprises any effect of chemicals and active substances on mammalian reproduction (fertility, weaning) and development (embryonal and fetal development). The investigations and the interpretation of the results should be related to all other pharmacological and toxicological data available to determine the risk of the test compound to humans. To allow detection of immediate and latent effects of exposure, the observations should cover one complete life cycle from the mature adult through all stages of development from conception of one generation to conception of the following generation(s).

Keywords

Toxicity Study Reproductive Toxicity OECD Guideline General Physical Condition Maternal Toxicity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References and Further Reading

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Experimental Toxicology and Ecology, GV/TEBASF SELudwigshafenGermany

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