Absorption: In Vivo Tests (Radiolabeled)

  • Volker Krone


The use of radiolabeled molecules allows a drug and its labeled metabolites to be followed throughout the body and excreta over time. The radioactivity concentration can be tracked in blood and plasma as well as in tissues. Whether the drug with its specific radioactivity administered to the body is completely captured can be proven by calculating the so-called mass balance.


Radioactivity Concentration Enterohepatic Circulation Placental Transfer Stomach Tube Collection Interval 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.DI & A DMPKSanofi Pharma Deutschland GmbHFrankfurtGermany

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