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Zebrafish in Drug Discovery: Safety Assessment

  • Adrian Hill

Abstract

Included in this review are a series of the more common larval and adult zebrafish safety screens that have been developed over the past decade. As such, this is not a comprehensive list but aims to highlight benefits, advances, and pitfalls of key screens related solely to the cardiovascular system and CNS, as well as provide comparisons to earlier models and alternative in vitro and in vivo screens.

Keywords

Conditioned Place Preference Danio Rerio Adult Zebrafish hERG Channel Zebrafish Larva 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Business Engagement & Innovation ServicesUniversity of NottinghamNottinghamUnited Kingdom

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