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Skin Pharmacology

  • Thais H. Sakuma
  • Hongbo Zhai
  • Howard Maibach
Reference work entry

Abstract

PURPOSE AND RATIONALE

Percutaneous absorption, also known as dermal or skin absorption, is a term that refers to the transport of a chemical from the outermost layer of the skin (stratum corneum) to the systemic circulation. Percutaneous absorption assays are essential for the safety assessment of chemicals making contact with the skin surface, such as pesticides, topically applied pharmaceuticals, industrial chemicals, and cosmetics, as well as in the development of drugs for dermal or transdermal application.

Keywords

Stratum Corneum Test Substance Sodium Lauryl Sulfate Skin Irritation Intradermal Injection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Department of DermatologyUC San FranciscoSan FranciscoUSA

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