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Essential Oils as Antimicrobial Agents

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Natural Products

Abstract

During the last decades, the limit of microbial diseases and infections has been exceeded dramatically. Several types of pathogenic microbes have been reported; however, some are being less infection responsible. Increase in disease infections in human and plants caused by pathogenic bacteria and fungi mainly occurs due to the development of new specific features in microbial majority, making them to adapt in any environmental condition. Resistance of these pathogens to commercial antibiotic drugs has emerged as a great health concern to the consumers. Diseases caused by bacteria and fungi and their resistant nature to antibiotics have played a vital role to increased rate in plant and human infectious diseases. Extensive use of antibiotics in several industries against hazardous bacteria and fungi has resulted in additional antibiotic resistance to these pathogens, which has become a matter of great concern to the public health. There has been an increasing concern worldwide on therapeutic values of natural products including essential oils. Hence, there are multitudes of potential useful bioactive substances to be derived from plants. With the recent trend of high percentage of resistance in microorganisms to the present-day antibiotics, search for new and effective drugs is a challenging task. This chapter discusses antimicrobial efficacy and suitability of plant essential oils against diverse range of microbial pathogens causing several diseases in human and agricultural industry. Also, a brief description of the chemical nature of essential oils, mode of antimicrobial action, their legal use in various beneficial industries, and the area for future research has been laid out.

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References

  1. Rabsch W, Tschape H, Andreas J, Baumler AJ (2001) Non-typhoidal salmonellosis: emerging problems. Microbes Infect 3:237

    Article  CAS  Google Scholar 

  2. Guarro J, Pujol I, Mayayo E (1999) In vitro and in vivo experimental activities of antifungal agents against Fusarium solani. Antimicrob Agents Chemother 43:1256

    CAS  Google Scholar 

  3. El-Gazzar EF, Marth EH (1975) Salmonellae, salmonellosis, and dairy foods: a review. J Dairy Sci 75:2327

    Article  Google Scholar 

  4. Ingroff AE (1998) In vitro activity of the new triazole voriconazole (UK-109,496) against opportunistic filamentous and dimorphic fungi and common and emerging yeast pathogens. J Clin Microbiol 36:198

    Google Scholar 

  5. Bajpai VK, Kang SC (2010) Antifungal activity of leaf essential oil and extracts of Metasequoia glyptostroboides Miki ex Hu. J Am Oil Chem Soc 87:327

    Article  CAS  Google Scholar 

  6. Burdon JJ (1993) The structure of pathogen populations in natural plant communities. Annu Rev Phytopathol 3:305

    Article  Google Scholar 

  7. Mead PS, Slutsker L, Detz V, McCaig LF, Breese JS, Shapiro C, Griffin PM, Tauxe RV (1999) Food-related illness and death in the United States. Emerg Infect Dis 5:607

    Article  CAS  Google Scholar 

  8. O’Brien TF (2002) Emergence, spread, and environmental effect of antimicrobial resistance: how use of an antimicrobial anywhere can increase resistance to any antimicrobial anywhere else. Clin Infect Dis 34:78

    Article  Google Scholar 

  9. Oussalah M, Caillet S, Sauciere L, Lacroix M (2007) Inhibitory effects of selected plant essential oils on the growth of four pathogenic bacteria: E. coli O157:H7, Salmonella typhimurium, Staphylococcus aureus and Listeria monocytogenes. Food Control 18:414

    Article  CAS  Google Scholar 

  10. Bajpai VK, Rahman A, Kang SC (2008) Chemical composition and inhibitory parameters of essential oil and extracts of Nandina domestica Thunb. to control food-borne pathogenic and spoilage bacteria. Int J Food Microbiol 125:117

    Article  CAS  Google Scholar 

  11. Bajpai VK, Rahman A, Kang SC (2007) Chemical composition and anti-fungal properties of the essential oil and crude extracts of Metasequoia glyptostroboides Miki ex Hu. Ind Crop Prod 26:28

    Article  CAS  Google Scholar 

  12. Conner DE (1993) Naturally occurring compounds. In: Davidson P, Branen AL (eds) Antimicrobials in foods. Marcel Dekker, New York, p 441

    Google Scholar 

  13. Exarchou V, Nenadis N, Tsimidou M, Gerothanassis IP, Troganis A, Boskou D (2002) Antioxidant activities and phenolic composition of extracts from Greek oregano, Greek sage and summer savory. J Agric Food Chem 50:5294

    Article  CAS  Google Scholar 

  14. Botsoglou NA, Govaris A, Botsoglou EN, Grigoropoulou S, Papageorgiou G (2003) Antioxidant activity of dietary oregano essential oil and alpha-tocopheryl acetate supplementation in long-term frozen stored turkey meat. J Agric Food Chem 2003:2930

    Article  Google Scholar 

  15. Gould GW (1999) Sous vide foods: conclusions of an ECFF botulinum working party. Food Control 10:47

    Article  Google Scholar 

  16. Davidson PM (1997) Chemical preservatives and natural antimicrobial compounds. In: Doyle MP, Beuchat LR, Mont-Ville TJ (eds) Food microbiology fundamentals and frontiers. ASM, Washington, DC, p 520

    Google Scholar 

  17. Board RG, Gould GW (1991) Future prospects. In: Gould NJR (ed) Food preservatives. Blackie, Glasgow, p 267

    Google Scholar 

  18. Skandamis P, Tsigarida E, Nychas GJE (2000) Differences in the behavior of oregano essential oil on Salmonella tymphimurium cells in liquid culture and within a gelatin gel. World J Microbiol Biotechnol 16:31

    Article  CAS  Google Scholar 

  19. Tassou C, Drosinos EH, Nychas GJE (1995) Effects of essential oil from mint (Mentha piperita) on Salmonella enteritidis and Listeria monocytogenes in model food systems at 4 and 10°C. J Appl Bacteriol 78:593

    Article  CAS  Google Scholar 

  20. Tsigarida E, Skandamis P, Nychas GJE (2000) Behaviour of Listeria monocytogenes and autochthonous flora on meat stored under aerobic,vacuum and modified atmosphere packaging conditions with or without the presence of oregano essential oil at 5°C. J Appl Microbiol 89:901

    Article  CAS  Google Scholar 

  21. Skandamis PN, Nychas GJE (2001) Effect of oregano essential oil on microbiological and physicochemical attributes of mince meat stored in air and modified atmospheres. J Appl Microbiol 91:1011

    Article  CAS  Google Scholar 

  22. Dorman HJD, Deans SG (2000) Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol 88:308

    Article  CAS  Google Scholar 

  23. Burt SA, Reinders RD (2003) Antibacterial activity of selected plant essential oils against Escherichia coli O157:H7. Lett Appl Microbiol 36:162

    Article  CAS  Google Scholar 

  24. Cox SD, Mann CM, Markham JL, Bell HC, Gustafson JE, Warmington JR, Wyllie SG (2000) The mode of antimicrobial action of the essential oil of Melaleuca alternifolia (tea tree oil). J Appl Microbiol 88:170

    Article  CAS  Google Scholar 

  25. Mejlholm O, Dalgaard P (2002) Antimicrobial effect of essential oils on the seafood spoilage micro-organism Photobacterium phosphoreum in liquid media and fish products. Lett Appl Microbiol 34:27

    Article  CAS  Google Scholar 

  26. Helander IM, Alakomi HL, Latva-Kala K, Mattila-Sandholm T, Pol I, Smid EJ, Gorris LGM, Vonwright A (1998) Characterization of the action of selected essential oil components on Gram-negative bacteria. J Agric Food Chem 46:3590

    Article  CAS  Google Scholar 

  27. Kim J, Marshall MR, Wei CI (1995) Antibacterial activity of some essential oil components against five foodborne pathogens. J Agric Food Chem 43:2839

    Article  CAS  Google Scholar 

  28. Bajpai VK, Rahman A, Choi UK, Youn SJ, Kang SC (2007) Inhibitory parameters of the essential oil and various extracts of Metasequoi glyptostroboides Miki ex Hu to reduce food spoilage and food-borne pathogens. Food Chem 105:1061

    Article  CAS  Google Scholar 

  29. Didry N, Dubreuil L, Pinkas M (1993) Antibacterial activity of thymol, carvacrol and cinnamaldehyde alone or in combination. Pharmazie 48:301

    CAS  Google Scholar 

  30. Salgueiro LR, Vila R, Tomi F, Figueiredo AC, Barroso JG, Canigueral S (1997) Variability of essential oils of Thymus caespititius from Portugal. Phytochemistry 45:307

    Article  CAS  Google Scholar 

  31. Venskutonis PR (1996) Effect of drying on the volatile constituents of thime (Thymus vulgaris L.) and sage (Salvia officinalis L.). Food Chem 2:219

    Google Scholar 

  32. Lambert RJW, Skandamis PN, Coote P, Nychas GJE (2001) A study of the minimum inhibitory concentration and mode of action of oregano essential oil, thymol and carvacrol. J Appl Microbiol 91:453

    Article  CAS  Google Scholar 

  33. Paster N, Menasherov M, Ravid U, Juven B (1995) Antifungal activity of oregano and thyme essential oils applied as fumigants against fungi attacking stored grain. J Food Protec 58:81

    CAS  Google Scholar 

  34. Marino M, Bersani C, Comi G (2001) Impedance measurements to study the antimicrobial activity of essential oils from Lamiaceae and Compositae. Int J Food Microbiol 67:187

    Article  CAS  Google Scholar 

  35. Bajpai VK, Dung NT, Kwon OJ, Kang SC (2008) Analysis and the potential applications of essential oil and leaf extracts of Silene armeria L. to control food spoilage and food-borne pathogens. Eur Food Res Technol 227:1613

    Article  CAS  Google Scholar 

  36. Bajpai VK, Rahman A, Dung NT, Huh MK, Kang SC (2008) In vitro inhibition of food spoilage and foodborne pathogenic bacteria by essential oil and leaf extracts of Magnolia liliflora Desr. J Food Sci 73:314

    Article  Google Scholar 

  37. Paranagama PA, Abeysekera KHT, Abeywickrama K, Nugaliyadd L (2003) Fungicidal and anti-aflatoxigenic effects of the essential oil of Cymbopogon citratus (DC.) Stapf. (lemongrass) against Aspergillus flavus Link. isolated from stored rice. Lett Appl Microbiol 37:86

    Article  CAS  Google Scholar 

  38. Deans SG, Sbodova KP (1990) The antimicrobial properties of marjoram (Origanum majorana L.) volatile oil. Flav Fragr J 5:187

    Article  Google Scholar 

  39. Burt SA (2004) Essential oils: their antibacterial properties and potential applications in foods-a review. Int J Food Microbiol 94:223

    Article  CAS  Google Scholar 

  40. Leistner L (1978) Hurdle effect and energy saving. In: Downey WK (ed) Foodquality and nutrition. Applied Science Publication, London, p 553

    Google Scholar 

  41. De Silva TK (ed) (1996) A manual on the essential oil industry. United Nations Industrial Development Organization, Vienna

    Google Scholar 

  42. Smid EJ, Gorris LGM (1999) Natural antimicrobials for food preservation. In: Rahman MS (ed) Handbook of food preservation. Marcel Dekker, New York, p 285

    Google Scholar 

  43. Al-Reza SM, Rahman A, Ahmed Y, Kang SC (2010) Inhibition of plant pathogens in vitro and in vivo with essential oil and organic extracts of Cestrum nocturnum L. Pesticide Biochem Physiol 96:86

    Article  CAS  Google Scholar 

  44. Van de Braak SAAJ, Leijten GCJJ (1999) Essential oils and oleoresins: a survey in the Netherlands and other major markets in the European Union. CBI. Centre for the promotion of imports from developing countries, Rotterdam, p 116

    Google Scholar 

  45. Deans SG, Ritchie G (1987) Antibacterial properties of plant essential oils. Int J Food Microbiol 5:165

    Article  Google Scholar 

  46. Carson CF, Riley TV (1995) Antimicrobial activity of the major components of the essential oil of Melaleuca alternifolia. J Appl Bacteriol 78:264

    Article  CAS  Google Scholar 

  47. Mourey A, Canillac N (2002) Anti-Listeria monocytogenes activity of essential oils components of conifers. Food Control 13:289

    Article  CAS  Google Scholar 

  48. Mahmoud SS, Croteau RB (2002) Strategies for transgenic manipulation of monoterpene biosynthesis in plants. Trends Plant Sci 7:366

    Article  CAS  Google Scholar 

  49. Bauer K, Garbe D (1985) Common fragrance and flavor materials. Preparation properties and uses. VCH Verlagsgesellschaft, Weinheim, p 213

    Google Scholar 

  50. Van Welie RTH (1997) Alle cosmetica ingredie¨nten en hun functies. Nederlandse Cosmetica Vereniging, Nieuwegein, p 126

    Google Scholar 

  51. Oosterhaven K, Poolman B, Smid EJ (1995) S-Carvone as a natural potato sprout inhibiting, fungistatic and bacteristatic compound. Ind Crop Prod 4:23

    Article  CAS  Google Scholar 

  52. Mendoza-Yepes MJ, Sanchez-Hidalgo LE, Maertens G, Marin-Iniesta F (1997) Inhibition of Listeria monocytogenes and other bacteria by a plant essential oil (DMC) in Spanish soft cheese. J Food Safety 17:47

    Article  CAS  Google Scholar 

  53. Cutter CN (2000) The antimicrobial effect of herb extracts against Escherichia coli O157:H7, Listeria monocytogenes, and Salmonella Typhimurium associated with beef. J Food Prot 63:601

    CAS  Google Scholar 

  54. Lopez P, Sanchez C, Battle R, Nerin C (2005) Solid- and vapor-phase antimicrobial activities of six essential oils: susceptibility of selected foodborne bacterial and fungal strains. J Agric Food Chem 53:6939

    Article  CAS  Google Scholar 

  55. Benkeblia N (2004) Antimicrobial activity of essential oil extracts of various onions (Allium cepa) and garlic (Allium sativum). Lebensm-Wiss u Technol 37:263

    Article  CAS  Google Scholar 

  56. Holley RA, Patel D (2005) Improvement in shelf-life and safety of perishable foods by plant essential oils and smoke antimicrobials. Food Microbiol 22:273

    Article  CAS  Google Scholar 

  57. Angioni A, Barra A, Cereti E, Barile D, Colsson JD, Arlorio M, Dessi S, Coroneo V, Cabras P (2004) Chemical composition, plant genetic differences, antimicrobial and antifungal activity investigation of the essential oil of Rosmarinus officinalis L. J Agric Food Chem 52:3530

    Article  CAS  Google Scholar 

  58. Bakkali F, Averbeck S, Averbeck D, Idaomar M (2008) Biological effects of essential oils – A review. Food Chem Toxicol 46:446

    Article  CAS  Google Scholar 

  59. Pichersky E, Noel JP, Dudareva N (2006) Biosynthesis of plant volatiles: Nature's diversity and ingenuity. Science 311:808

    Article  CAS  Google Scholar 

  60. Carson CF, Mee BJ, Riley TV (2002) Mechanism of action of Melaleuca alternifolia (tea tree) oil on Staphylococcus aureus determined by time-kill, lysis, leakage, and salt tolerance assays and electron microscopy. Antimicrob Agents Chemother 46:1914

    Article  CAS  Google Scholar 

  61. Knobloch K, Weigand H, Weis N, Schwarm HM, Vigenschow H (1986) Action of terpenoids on energy metabolism. In: Brunke EJ (ed) Progress in essential oil research: 16th International symposium on essential oils, De Gruyter, Berlin, p 429

    Google Scholar 

  62. Sikkema J, de Bont JAM, Poolman B (1995) Mechanisms of membrane toxicity of hydrocarbons. Microbiol Rev 59:201

    CAS  Google Scholar 

  63. Rasooli I, Rezaei MB, Allameh A (2006) Ultrastructural studies on antimicrobial efficacy of thyme essential oils on Listeria monocytogenes. Int J Infect Dis 10:236

    Article  Google Scholar 

  64. Ultee A, Slump RA, Steging G, Smid EJ (2000) Antimicrobial activity of carvacrol toward Bacillus cereus on rice. J Food Prot 63:620

    CAS  Google Scholar 

  65. Juven BJ, Kanner J, Schved F, Weisslowicz H (1994) Factors that interact with the antibacterial action of thyme essential oil and its active constituents. J Appl Bacteriol 76:626

    Article  CAS  Google Scholar 

  66. Wendakoon CN, Sakaguchi M (1995) Inhibition of amino acid decarboxylase activity of Enterobacter aerogenes by active components of spices. J Food Prot 58:280

    CAS  Google Scholar 

  67. Fisher K, Phillips C (2008) Potential antimicrobial uses of essential oils in food: is citrus the answer? Trends Food Sci Technol 19:156

    Article  CAS  Google Scholar 

  68. Uribe S, Ramirez J, Pena A (1985) Effects of beta-pinene on yeast membrane functions. J Bacteriol 161:1195

    CAS  Google Scholar 

  69. Lunde CS, Kubo I (2000) Effect of polygodial on the mitochondrial ATPase of Saccharomyces cerevisiae. Antimicrob Agents Chemother 44:1943

    Article  CAS  Google Scholar 

  70. Oussalah M, Caillet S, Lacroix M (2006) Mechanism of action of Spanish oregano, Chinese cinnamon, and savory essential oils against cell membranes and walls of Escherichia coli O157:H7 and Listeria monocytogenes. J Food Prot 69:1046

    Google Scholar 

  71. Davidson PM, Parish ME (1989) Methods for testing the efficacy of food antimicrobials. Food Technol 43:148

    CAS  Google Scholar 

  72. Gill AO, Delaquis P, Russo P, Holley RA (2002) Evaluation of antilisterial action of cilantro oil on vacuum packed ham. Int J Food Microbiol 73:83

    Article  CAS  Google Scholar 

  73. Yoon JI, Bajpai VK, Kang SC (2011) Synergistic effect of nisin and cone essential oil of Metasequoia glytostroboides Miki ex Hu against Listeria monocytogenes in milk samples. Food Chem Toxicol 49:109

    Article  CAS  Google Scholar 

  74. Delaquis PJ, Stanich K, Girard B, Mazza G (2002) Antimicrobial activity of individual mixed fractions of dill, cilantrol, coriander and eucalyptus essential oils. Int J Food Microbiol 74:101

    Article  CAS  Google Scholar 

  75. Moleyar V, Narasimham P (1992) Antibacterial activity of essential oil components. Int J Food Microbiol 16:337

    Article  CAS  Google Scholar 

  76. Al-Reza SM, Rahman A, Kang SC (2009) Chemical composition and inhibitory effect of essential oil and organic extracts of Cestrum nocturnum L. on food-borne pathogens. Int J Food Sci Technol 44:1176

    Article  CAS  Google Scholar 

  77. Al-Reza SM, Rahman A, Lee JG, Kang SC (2010) Potential roles of essential oil and organic extracts of Zizyphus jujuba in inhibiting food-borne pathogens. Food Chem 119:981

    Article  CAS  Google Scholar 

  78. Rahman A, Lee JG, Kang SC (2009) In vitro control of food borne and food spoilage bacteria by essential oil and ethanol extracts of Lonicera japonica Thunb. Food Chem 116:670

    Article  CAS  Google Scholar 

  79. Bajpai VK, Al-Reza SM, Choi UK, Lee JH, Kang SC (2009) Chemical composition, antibacterial and antioxidant activities of leaf essential oil and extracts of Metasequoia glyptostroboides Miki ex Hu. Food Chem Toxicol 47:1876

    Article  CAS  Google Scholar 

  80. Grbic ML, Stupar M, Vukojevic J, Sokovic M, Misic D, Grubisic D, Ristic M (2008) Antifungal activity of Nepeta rtanjensis essential oil. J Serb Chem Soc 73:961

    Article  CAS  Google Scholar 

  81. Sartoratto A, Machado AM, Delarmelina C, Figueira GM, Duarte MT, Rehder VG (2004) Composition and antimicrobial activity of essential oils from aromatic plants used in Brazil. Braz J Microbiol 35:275

    Article  CAS  Google Scholar 

  82. Pinto E, Pina-Vaz C, Salgueiro L, Goncalves MJ, Costa-de-Oliveira S, Cavaleiro C, Palmeira A, Rodrigues A, Martinez-de-Oliveira J (2006) Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillus and dermatophyte species. J Med Microbiol 55:1367

    Article  CAS  Google Scholar 

  83. Chuang PH, Lee CW, Chou JY, Murugan M, Shieh BJ, Chen HM (2007) Antifungal activity of crude extracts and essential oils of Moringa oleifera Lam. Biores Technol 98:232

    Article  CAS  Google Scholar 

  84. Taran M, Ghasempour HR, Shirinpour E (2010) Antimicrobial activity of essential oils of Ferulago angulata subsp. Carduchorum. J Microbiol 3:10

    Google Scholar 

  85. Prabuseenivasan S, Jayakumar M, Ignacimuthu S (2006) In vitro antimicrobial activity of some plant essential oil. BMC Compl Alter Med 6:1

    Article  Google Scholar 

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Authors and Affiliations

  1. Laboratory of Plant Molecular Physiology, School of Biotechnology, Yeungnam University, 241-1 Dae-dong, 712-749, Gyeongsan, Gyeongbuk, Korea

    Dr. Prof. Vivek K. Bajpai & Ajay Sharma

  2. Department of Food Science and Technology, Yeungnam University, 712-749, Gyeongsan, Gyeongbuk, Korea

    Shruti Shukla

Authors
  1. Dr. Prof. Vivek K. Bajpai
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  2. Shruti Shukla
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  3. Ajay Sharma
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Correspondence to Vivek K. Bajpai .

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Editors and Affiliations

  1. Botany Department, M.L. Sukhadia University, Durga Nursery Road, Udaipur, 313001, Rajasthan, India

    Kishan Gopal Ramawat

  2. Institute of Vine and Wine Sciences, Biological-Active Plant Substances Study, University of Bordeaux, 210 Chemin de Leysotte CS 50008, Villenave d'Ornon, 33882, France

    Jean-Michel Mérillon

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Bajpai, V.K., Shukla, S., Sharma, A. (2013). Essential Oils as Antimicrobial Agents. In: Ramawat, K., Mérillon, JM. (eds) Natural Products. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-22144-6_169

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