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Cell Damage

  • Susanne ModrowEmail author
  • Falke Dietrich
  • Uwe Truyen
  • Hermann Schätzl
Reference work entry

Abstract

The disease symptoms associated with viral infections are based on virus-mediated damage to the infected cells and tissues. A distinction is made between direct cell destruction as a result of viral replication, as found in picornaviruses ( Sect. 14.1), and indirect cell destruction, which is generally caused by immunopathological damage. The latter is from damaging effects of the immune response, which was originally developed by the organism for the clearance of pathogens ( Chaps. 7 and  8). For example, in the course of hepatitis B infections, liver cells are attacked and lysed by cytotoxic T cells; therefore, the immune system itself contributes decisively to the emergence of symptoms ( Sect. 19.1).

Keywords

Human Immunodeficiency Virus Respiratory Syncytial Virus Viral Genome Barr Virus Subacute Sclerosing Panencephalitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Further Reading

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Susanne Modrow
    • 1
    Email author
  • Falke Dietrich
    • 2
  • Uwe Truyen
    • 3
  • Hermann Schätzl
    • 4
  1. 1.Inst. Medizinische, Mikrobiologie und HygieneUniversität RegensburgRegensburgGermany
  2. 2.MainzGermany
  3. 3.Veterinärmedizinische Fak., Inst. Tierhygiene undUniversität LeipzigLeipzigGermany
  4. 4.Helmholtz Zentrum München, Institut für VirologieTU MünchenMünchenGermany

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