Viruses with a Double-Stranded DNA Genome

  • Susanne ModrowEmail author
  • Falke Dietrich
  • Uwe Truyen
  • Hermann Schätzl
Reference work entry


There are many viruses with a double-stranded DNA genome that are known to infect mammals. They are subdivided into seven virus families: Hepadnaviridae, Polyomaviridae, Papillomaviridae, Adenoviridae, Herpesviridae, Poxviridae and Asfarviridae. With the exception of the families Poxviridae and Asfarviridae, all families have members that can cause persistent infections in humans or animals. Hepadnaviruses, polyomaviruses, papillomaviruses and herpesviruses are causally related to human cancers. This suggests that double-stranded DNA viruses have many ways to regulate and influence cell division. Hepadnaviruses, which are described at the beginning of this chapter, are closely related to retroviruses. Many details of their replication cycle suggest that they have evolved from retroviruses.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Susanne Modrow
    • 1
    Email author
  • Falke Dietrich
    • 2
  • Uwe Truyen
    • 3
  • Hermann Schätzl
    • 4
  1. 1.Inst. Medizinische, Mikrobiologie und HygieneUniversität RegensburgRegensburgGermany
  2. 2.MainzGermany
  3. 3.Veterinärmedizinische Fak., Inst. Tierhygiene undUniversität LeipzigLeipzigGermany
  4. 4.Helmholtz Zentrum München, Institut für VirologieTU MünchenMünchenGermany

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