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SWI/SNF

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Encyclopedia of Cancer
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Definition

Highly conserved multiproteic structures involved in the ATP-dependent chromatin remodeling. Among the core subunits of SWI/SNF, hSNF5/INI1 is responsible for the oncogenesis of rhabdoid tumors.

hSNF5/INI1/SMARCB1 Tumor Suppressor Gene

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© 2011 Springer-Verlag Berlin Heidelberg

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(2011). SWI/SNF. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16483-5_5612

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