Definition
Refers to the two-step process of delivering a gene to tumor cells that is able to transform a nontoxic prodrug into a toxic metabolite and thus killing the cells. Transfer of a gene which, when expressed in cells, activates a normally nontoxic prodrug to a toxic form.
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© 2011 Springer-Verlag Berlin Heidelberg
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(2011). Suicide Gene Therapy. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16483-5_5558
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DOI: https://doi.org/10.1007/978-3-642-16483-5_5558
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Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-16482-8
Online ISBN: 978-3-642-16483-5
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